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    Anti-Aging Peptides

    Peptides researched for their potential to slow biological aging markers.

    CJC-1295

    Medium Evidence

    A growth hormone releasing hormone analog studied for stimulating growth hormone secretion.

    Ipamorelin

    Medium Evidence

    A selective growth hormone secretagogue studied for targeted GH release with fewer side effects than other GH peptides.

    GHK-Cu

    High Evidence

    A naturally occurring copper-binding peptide studied for skin regeneration, wound healing, and anti-aging effects.

    Epithalon

    Low Evidence

    A tetrapeptide studied for its potential to activate telomerase and influence biological aging markers.

    MOTS-c

    Low Evidence

    A mitochondrial-derived peptide studied for metabolic regulation, exercise mimetic effects, and longevity.

    SS-31

    High Evidence

    A mitochondria-targeted peptide FDA-approved as FORZINITY (elamipretide) for Barth syndrome in September 2025 — the first FDA-approved mitochondrial-targeted therapeutic.

    Dihexa

    Low Evidence

    A hexapeptide analog studied for cognitive enhancement via hepatocyte growth factor pathway activation.

    FOXO4-DRI

    Low Evidence

    A senolytic peptide designed to selectively clear senescent cells by disrupting FOXO4-p53 interaction.

    Tesamorelin

    High Evidence

    A GHRH analog FDA-approved for reducing visceral fat in HIV-associated lipodystrophy.

    Sermorelin

    Medium Evidence

    A GHRH analog previously FDA-approved for growth hormone deficiency diagnosis and treatment.

    CJC-1295 (DAC)

    Medium Evidence

    A long-acting GHRH analog with an extended half-life due to its Drug Affinity Complex modification.

    GHRP-2

    Medium Evidence

    A synthetic hexapeptide growth hormone secretagogue studied for its potent stimulation of growth hormone release via the ghrelin receptor.

    Thymalin

    Low Evidence

    A thymic peptide preparation studied for immune system rejuvenation and age-related immune decline.

    NAD+

    Medium Evidence

    A coenzyme essential for cellular energy production, studied for anti-aging and metabolic support.

    Pinealon

    Low Evidence

    A short bioregulatory peptide studied for neuroprotective effects and cognitive support in aging.

    SNAP-8

    Medium Evidence

    A cosmetic peptide studied for reducing the appearance of wrinkles by modulating muscle contraction signaling.

    GLOW

    Low Evidence

    A multi-peptide blend of BPC-157, TB-500, and GHK-Cu formulated for tissue repair and skin rejuvenation.

    Klotho (Alpha-Klotho)

    Low Evidence

    A naturally occurring longevity hormone (secreted alpha-klotho) being studied for cognition and brain aging; a single low-dose injection improved memory in aged monkeys, and a first-in-human Phase 1 trial in older adults is underway.

    Humanin

    Low Evidence

    An endogenous mitochondrial-derived peptide studied for neuroprotection, cellular stress resistance, and longevity, whose blood levels fall with age and are elevated in centenarians.

    Abaloparatide

    High Evidence

    Abaloparatide (Tymlos) is a synthetic 34-amino-acid analog of parathyroid hormone-related protein, PTHrP(1-34), engineered to bind the PTH1 receptor with a strong preference for its transient RG conformation rather than the long-lived R0 conformation favored by teriparatide. That receptor bias produces a shorter burst of signaling per injection - enough to drive osteoblast activity, but short enough to limit the bone resorption and calcium mobilization that follow a prolonged signal. In the 18-month Phase 3 ACTIVE trial in 2,463 postmenopausal women, abaloparatide 80 mcg daily reduced new morphometric vertebral fractures by 86% versus placebo, alongside significant reductions in nonvertebral, major osteoporotic and clinical fractures. The FDA approved Tymlos in April 2017; in December 2021 the osteosarcoma boxed warning and the two-year cumulative lifetime limit were both removed from the label.

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