Anti-Aging Peptides
Peptides researched for their potential to slow biological aging markers.
CJC-1295
Medium EvidenceA growth hormone releasing hormone analog studied for stimulating growth hormone secretion.
Ipamorelin
Medium EvidenceA selective growth hormone secretagogue studied for targeted GH release with fewer side effects than other GH peptides.
GHK-Cu
High EvidenceA naturally occurring copper-binding peptide studied for skin regeneration, wound healing, and anti-aging effects.
Epithalon
Low EvidenceA tetrapeptide studied for its potential to activate telomerase and influence biological aging markers.
MOTS-c
Low EvidenceA mitochondrial-derived peptide studied for metabolic regulation, exercise mimetic effects, and longevity.
SS-31
High EvidenceA mitochondria-targeted peptide FDA-approved as FORZINITY (elamipretide) for Barth syndrome in September 2025 — the first FDA-approved mitochondrial-targeted therapeutic.
Dihexa
Low EvidenceA hexapeptide analog studied for cognitive enhancement via hepatocyte growth factor pathway activation.
FOXO4-DRI
Low EvidenceA senolytic peptide designed to selectively clear senescent cells by disrupting FOXO4-p53 interaction.
Tesamorelin
High EvidenceA GHRH analog FDA-approved for reducing visceral fat in HIV-associated lipodystrophy.
Sermorelin
Medium EvidenceA GHRH analog previously FDA-approved for growth hormone deficiency diagnosis and treatment.
CJC-1295 (DAC)
Medium EvidenceA long-acting GHRH analog with an extended half-life due to its Drug Affinity Complex modification.
GHRP-2
Medium EvidenceA synthetic hexapeptide growth hormone secretagogue studied for its potent stimulation of growth hormone release via the ghrelin receptor.
Thymalin
Low EvidenceA thymic peptide preparation studied for immune system rejuvenation and age-related immune decline.
NAD+
Medium EvidenceA coenzyme essential for cellular energy production, studied for anti-aging and metabolic support.
Pinealon
Low EvidenceA short bioregulatory peptide studied for neuroprotective effects and cognitive support in aging.
SNAP-8
Medium EvidenceA cosmetic peptide studied for reducing the appearance of wrinkles by modulating muscle contraction signaling.
GLOW
Low EvidenceA multi-peptide blend of BPC-157, TB-500, and GHK-Cu formulated for tissue repair and skin rejuvenation.
Klotho (Alpha-Klotho)
Low EvidenceA naturally occurring longevity hormone (secreted alpha-klotho) being studied for cognition and brain aging; a single low-dose injection improved memory in aged monkeys, and a first-in-human Phase 1 trial in older adults is underway.
Humanin
Low EvidenceAn endogenous mitochondrial-derived peptide studied for neuroprotection, cellular stress resistance, and longevity, whose blood levels fall with age and are elevated in centenarians.
Abaloparatide
High EvidenceAbaloparatide (Tymlos) is a synthetic 34-amino-acid analog of parathyroid hormone-related protein, PTHrP(1-34), engineered to bind the PTH1 receptor with a strong preference for its transient RG conformation rather than the long-lived R0 conformation favored by teriparatide. That receptor bias produces a shorter burst of signaling per injection - enough to drive osteoblast activity, but short enough to limit the bone resorption and calcium mobilization that follow a prolonged signal. In the 18-month Phase 3 ACTIVE trial in 2,463 postmenopausal women, abaloparatide 80 mcg daily reduced new morphometric vertebral fractures by 86% versus placebo, alongside significant reductions in nonvertebral, major osteoporotic and clinical fractures. The FDA approved Tymlos in April 2017; in December 2021 the osteosarcoma boxed warning and the two-year cumulative lifetime limit were both removed from the label.
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