Cognition Peptides
Peptides studied for potential cognitive enhancement and neuroprotection.
Selank
Medium EvidenceA synthetic peptide analog of tuftsin studied for anxiolytic and nootropic properties.
Semax
Medium EvidenceA synthetic peptide derived from ACTH, studied for cognitive enhancement and neuroprotective effects.
Dihexa
Low EvidenceA hexapeptide analog studied for cognitive enhancement via hepatocyte growth factor pathway activation.
Cerebrolysin
Medium EvidenceA porcine brain-derived peptide mixture approved in some countries for stroke recovery and neurodegenerative conditions.
Pinealon
Low EvidenceA short bioregulatory peptide studied for neuroprotective effects and cognitive support in aging.
P21
Medium EvidenceAn 11-amino-acid CNTF-derived peptide studied for its ability to upregulate BDNF expression and promote neurogenesis in cognitive decline models.
Klotho (Alpha-Klotho)
Low EvidenceA naturally occurring longevity hormone (secreted alpha-klotho) being studied for cognition and brain aging; a single low-dose injection improved memory in aged monkeys, and a first-in-human Phase 1 trial in older adults is underway.
Davunetide
Low EvidenceAn eight-amino-acid ADNP-derived peptide studied for microtubule stabilization, tau-related neuroprotection, and rare ADNP syndrome.
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