Gut Health Peptides

A pentadecapeptide derived from human gastric juice, studied for tissue repair and gut-protective properties.

A tripeptide derived from alpha-MSH, studied for anti-inflammatory and gut-protective properties.

A synthetic peptide tight junction regulator in clinical trials for celiac disease, designed to prevent intestinal permeability caused by gluten exposure.

A long-acting, once-weekly glucagon-like peptide-2 (GLP-2) analog that boosts intestinal absorption in short bowel syndrome, aiming to reduce dependence on IV (parenteral) nutrition; in Phase 3 development with a confirmatory trial required by the FDA.

A long-acting, once-weekly dual GLP-1 and GLP-2 receptor agonist peptide (Zealand Pharma) developed for obesity, uniquely pairing GLP-1-driven weight loss with GLP-2 activation intended to improve intestinal barrier function and reduce obesity-related low-grade inflammation; development was paused in November 2025.